The themes of the GIGA-Research research unit cover the field of biomedical sciences in the broad sense of the term. There are the following themes: cancer, neuroscience, immunity, inflammation and infections, cardiovascular sciences, medical genomics, molecular biology of disease, medicine in silico and imaging in vivo, and cyclotron. All GIGA-Research researchers are associated with one of these thematic units (UT), thus allowing for effective collaborations between researchers, the development of joint seminars and, above all, to make it easy to arrange an assessment of the research according to well-defined themes.
The FARAH is the new Structural interdisciplinary research centre of the Faculty of Veterinary Medicine of the University of Liège, which manages the structural resources of the institute dedicated to research. FARAH means "Fundamental and Applied Research for Animals & Health". The activities carried out by the members of FARAH belong to one of these three specialised sectors: comparative veterinary medicine, sustainable animal production and veterinary public health.
MARU - Motion Analysis Research Unit
The Motion Analysis Research Unit is based on motion analysis to explain different human, animal or non-living behaviour patterns. The research carried out within the unit covers a wide variety of themes that gives it a multidisciplinary character (physiotherapists, doctors, engineers, psychologists, veterinarians, physical trainers). Three main themes structure the research activity: the optimisation of sports performance: improvement of the movement, technique, prevention of injuries and accompaniment of return to the field of the injured athlete (amateur or professional), the clinical evaluation: prediction and prevention of risks, characterisation of a pathology, evaluation of the effect of active and/or medicinal products, and modelling: development of tools intended to replace certain expensive, invasive or impossible to achieve experimental phases
The "Health and Society" interfaculty research unit looks at the place occupied by the user in health systems through the development of a real "health democracy". This issue requires an interdisciplinary approach that focuses on the evolving interactions between the user, the health professional and the caregiver. This unit includes researchers in medicine, public health, mobility science, psychology, speech therapy and sociology. It will set up projects focusing on three defined axes: a user-centred axis, a focus on the health professional and the nursing staff, and a focus on health policies.
The research unit and methodology Biostatistics is a transversal support structure at the teaching level as well as at the research level in the Faculty of Medicine. The research activities revolve around: 1) the supervision/co-direction of end of year works and doctoral theses in the field of (or involving its use) biostatistics; 2) the development of research projects on current statistical themes such as the analysis of (incomplete) longitudinal data, limited data, joint modelling, the theme of medication compliance and its integration into pharmacokinetic, pharmacodynamic and pharmacoeconomic models; 3) the application and development of statistical methods meeting the needs of research projects and studies.
Research at the Centre interfacultaire des Biomatériaux (Interfaculty Center for Biomaterials, CEIB) covers areas such as: the synthesis and characterisation of materials (polymer, metal, ceramic, biopolymers), the treatment of materials (dispersed materials - micro nanoparticles...- hydrogels, porous media, surface coating, assays - in vitro, in vivo) and preclinical and clinical trials. The main research themes combine the immobilisation of drugs for both pharmaceutical applications (improvement of drug absorption, continuous drug delivery, drug targeting) and for the functionalisation of biomaterials (improvement of tissue engineering) .
The Centre Interdisciplinaire de Recherche sur le Médicament (Interdisciplinary Centre for Drug Research, CIRM) is a multidisciplinary research unit that investigates all major aspects of drug design. Research activities range from the discovery of new drug targets and the design or identification of major compounds to their formulation and testing. The approaches used include pre-clinical models in vitro (membranes and cells) and in vivo (small animals), modern analytical tools, but also innovative metabolomic and proteomic approaches. Patient-oriented research focuses on pharmacokinetics, clinical biology, toxicology, microbiology, pharmaceutical care and personalised medicine.
dBRU- Dental biomaterials research unit
The d-BRU is specialised in Biomaterials (particular dental), from their in vitro and in vivo studies to clinical research. Research revolves around 2 research focuses: implantable biomaterials on the one hand, and restorative biomaterials on the other. The first focus is more particularly dedicated to tissue regeneration biomaterials and dental implants, as well as their biological interaction with the living tissue, whereas the second focus studies the biomaterials intended for the restoration and regeneration of dental tissues, as well as prosthetic biomaterials in generals, whether dental or for implant. Research in dental biomaterials is characterised by its interdisciplinary and translational nature.
The central theme of this research unit is revalidation - physical therapy It is dedicated to the field of Evaluation and Revalidation in multiple components (thematic), and aims to develop a preventive and/or therapeutic treatment, for all patients consulting the service of Medicine of the locomotor apparatus of the University Hospital of Liège. It addresses the following specific topics: muscles - tendons - sports - shoulders; rachis; EMG - neurological revalidation; oncology (multidisciplinary oncology rehabilitation); bone - cartilage (osteoporosis, osteoarthritis).
Pedagogy of morphological sciences
The Research Unit for the Pedagogy of Morphological Sciences is based on spatial vision skills in the initial context of the life sciences. Through its research, it aims to better understand the fine processes of acquiring these skills, to develop and study the tools and ideal framework for their acquisition and evaluation. In a fast-moving world where the image is predominant and in ever-new forms, it seeks to analyse the exact needs of training in the mastery of this medium in accordance with the needs of the actors of the health of the future.
Primary care and health
The research themes addressed by the Primary Care and Health research unit concern, on the one hand, organisational aspects of the Belgian health system and the positioning of the discipline of general medicine within this system, and, on the other hand, aspects more related to the care of patients in the health system. Finally, another major aspect is that of medical pedagogy.
The Psychoneuroendocrinology unit develops its research along 4 axes. 1) Neuropeptides and neuroscience: role of neuropeptides in the response to psychosocial stress and their impact on psychiatric vulnerability; 2) Development of an eLogBook: digital logbook for clinical teachers and students in the context of internships in psychiatry; 3) Belgian BioElectroMagnetics Group (BBEMG): study on idiopathic environmental intolerance attributed to electricity; 4) Mediatisation of mental health: ethical reflection, therapeutic workshops for the general public, popular lectures, bibliotherapy.
The PsyNCog faculty research unit is defined by a multidisciplinary approach to the study of human cognition. The unit combines experimental behavioural procedures with neuroscientific methods, such as electroencephalography, transcranial electrical stimulation and functional neuroimaging.
Research Unit in Biology and Developmental Medicine
The Research Unit in Biology and Development Medicine has as its main research theme the questions that concern the crucial period of development, from conception to adolescence, in a predominantly clinical orientation and with the perspective of the study of the early origin of diseases of adulthood. More specifically, it develops its research and its collaborations through the following axes: reproduction, nutrition, growth, neuro-development, inflammation, pharmacokinetics.
The Unité de Recherche sur l’Os et le Cartilage (UROC, Bone and Cartilage Research Unit) specialises in the study of the pathophysiological mechanisms of osteoarthritis and in the pre-clinical and clinical study of anti-osteoarthritis drugs. More particularly, it studies, on original cell culture models (chondrocytes, osteoblasts and human synoviocytes) and animal models (osteoarthritis induced in the rabbit and spontaneous osteoarthritis in the guinea pig), the mechanisms of action of the drugs used in the osteoarthritis treatment and participates, in collaboration with the pharmaceutical industry, in the development of new molecules.
The Urology Unit investigates the following research themes: 1) Urologic oncology: clinical studies in the field of treatment of prostate and bladder cancer, evaluation of the efficacy and safety of intermittent hormone therapy in prostate cancer, identification of prognostic factors in prostate cancer, search for diagnostic markers and prognosis of non-invasive urothelial carcinoma of the bladder; 2) Functional Urology and Urogynecology: development and evaluation of new surgical techniques for the treatment of urinary incontinence in both women and men, vaginal prolapse; 3) sexual impotence; 4) Urinary lithiasis; 5) Neuro-urology.
The work of URSAPES focuses, through observational, analytical, interventional and evaluative studies, on the setting up of reflections, procedures and tools allowing a better understanding of the determinants of the evolution of the states of health in the goal of fostering ageing free from physical and mental disabilities. Currently, the research of this unit focuses mainly, but not exclusively, on pathologies or health conditions related to ageing of the musculoskeletal system such as osteoporosis, osteoarthritis, sarcopenia, fragility, undernutrition, or, still yet, falls. The cognitive aspects of ageing are the subject of a longer-term research project.
Facilities and equipment
This research platform, which depends on the TERRA research unit (Gembloux), promotes projects that consider agroecosystems as entities and stimulates the development of tools, techniques and knowledge to improve the overall performance of agroecosystems in terms of ecosystemic services.
The CART's missions are: to develop new concepts in analytical chemistry and data analysis, to lead research in the field of organic and inorganic compound analysis in foodstuffs, in animal products and in other biological and environmental materials, to carry out, on behalf of third parties, studies and analyses on organic and inorganic pollutants in foodstuffs, in animal products and in other biological and environmental materials, and to lead research on the effects of compounds and on their interactions with biological systems.
The Centre d'ingénierie des protéines (CIP, Protein Engineering Centre) is a multidisciplinary research centre. The Centre offers complementary approaches for analysing the structural and functional relationships of proteins. Nine closely-knit research teams form the centre provide cutting-edge expertise, from isolated proteins to integrated cellular networks, with particular reference to antibiotic resistance. The Centre also manages two technology platforms for expression, purification and protein analysis, accessible to both academic and commercial partners.
The CREMAN is the nuclear magnetic resonance centre of the University of Liège. Its missions include: coordination, maintenance and evolution of all NMR equipment, present or future, at the University of Liège, recording and interpretation of NMR spectra for any interested user, affiliated or not with the University of Liège, the instruction and training of new operators and the promotion of NMR science and technology through the organisation of scientific meetings and training workshops for the academic community or industrial partners.
CARE Foodislife's general objective is to strengthen GxABT's expertise in agro-resource valorisation. More precisely, it is a question of carrying out the steps of splitting up agro-resources, of purification, of transformation, and of fermentation, which constitute a key step for the development of biomolecules, both from a research perspective and from the perspective of supporting business development
GIGA's technological platform is the result of the pooling of a set of technological and human resources in order to offer cutting-edge services to researchers from the academic and industrial worlds. It brings together advanced technologies and high-level skills in the following areas: genomics, proteomics, cell imaging, preclinical and clinical, flow cytometry, immunohistochemistry, viral vectors, bioinformatics (genomics and imaging) and animal experimentation (Zebrafish and mice). In order to remain at the forefront of innovation and meet the challenges proposed by scientists and companies, the ERDF has enabled the platforms to hire experts in the various fields as well as the acquisition of exceptional equipment (BIOMED HUD Technology Support).
The experimental farm
The experimental culture farm is located in Gembloux, where roughly 50ha are dedicated to agricultural research testing. The soil has a clay texture (mainly Aba soils) The experimental farm is divided into several experimental areas with various research objectives.
CARE - FEPEX
CARE-FEPEX (Cellule d'Appui à la Recherche et à l'Enseignement - Ferme Pédagogique et Expériale, Support Unit for Research and Teaching - Pedagogical and Experimental Farm) provides support and assistance in veterinary research projects involving large laboratory animals. CARE-FEPEX implements all aspects related to the housing of production animals used in scientific projects and offers logistic and animal management solutions in the conduct of your study.
CARE - Medicale simulation center (CARESIM)
Robotein provides an automated analysis of biophysical protein, as well as screening for an optimal cloning and the expression of genes both in bacteria and yeast, and the purification of proteins. The broadband screening approach is used to optimise downstream labor-intensive stages, namely large-scale production and detailed biochemical and biophysical studies.
Alain Vanderplasschen is a professor at the Faculty of Veterinary Medicine at the University of Liège where he directs the Laboratory of Immunology and Vaccinology. He is the first researcher to win the GSK Vaccines Award.
Hosting a multidisciplinary research, the Human Movement Analysis Laboratory makes it possible, for example, to decipher walking from the point of view of applied sciences, medicine, psychology and veterinary medicine.
Located in the heart of the University of Liège (Belgium) and physically integrated into the University Hospital (CHU) of Liège, the GIGA is a major centre for research and activity development in the field of biotechnologies.