Interreg Meuse-Rhine (NL-BE-DE)
The Interreg Meuse-Rhine (EMR) program supports cross-border cooperation between the border regions of Belgium, Germany and the Netherlands, and more specifically between 5 regions: the Provinces of Limburg in Belgium and the Netherlands, the Province of Liège (BE), NordRhein-Westfalen (DE) and Rheinland-Pfalz (DE). For the 2021-2027 programming period, a total of 176 million euros will be available for cross-border projects, of which 125 million euros will be provided by the European Union. The remainder of the funding will be provided by regional co-financing from the Netherlands, Belgium and Germany, or by the applicant's own resources.
Interreg Meuse-Rhine has identified five major societal challenges in its region. Its program aims to improve the lives of the region's inhabitants and have a real impact on issues such as industrial transition, green transformation, health, tourism and cooperation.
Through Interreg EMR, the University of Liège is actively involved in projects aimed at making the Euregio Meuse-Rhine more attractive, greener, more social, closer to citizens and with better cross-border governance.
Interreg VI Meuse-Rhine project coordinated by ULiège
Acronym |
Title & Summary |
ULiègecoordinator |
| IMPRESS | The IMPRESS project aims to develop and validate an implementation toolkit for three previously validated safety interventions. IMPRESS explores the conditions for implementation, an aspect that has received little attention in the IMR but has recently been promoted by the WHO and the OECD. Another novel feature is the collaborative development with patients, who are involved as decision-makers to ensure the relevance and sustainability of the initiatives. By strengthening skills, cooperation, and learning across countries, IMPRESS directly contributes to the IMR’s challenge: healthier citizens. The project aims to improve access to safe care, support staff resilience, and promote the cross-border transfer of health innovations. The primary focus is on the patient-caregiver partnership working together to strengthen safety and resilience. The pilot phase will involve at least ten sites in the IMR, 300 professionals, and 1,500 patients, prior to wider rollout. |
Méryl Paquay |
| NBS4U | Urban areas in the Meuse-Rhine region are highly vulnerable to climate-related risks. In Belgium, extreme precipitation is projected to increase by 7% by 2030–2060 and by 14% by 2060–2080. The number of heat waves will rise from 2 per year under current climate conditions to 5–11 per year in the future. Climate risks are amplified in urban areas by the urban heat island effect, which leads to an increase in surface temperature (+7 °C) and air temperature (+2–3 °C). All regions and cities in the Meuse-Rhine region face similar climate challenges. NBS4U will provide a practical toolkit for evaluating and comparing nature-based solutions (NBS) suitable for urban areas, covering urban, peri-urban, and village settings. The tool will help identify optimal locations for implementing de-impermeabilization measures. The project will monitor the observed effects of NBS implemented in 7 living labs dedicated to local climate adaptation and will propose solutions to engage local communities, both private and public, in these projects. The living labs are designed as a cross-border community of practice, involving various pilot actions (green roofs and walls, de-impermeabilization, swales, etc.) to share experience and technical support among municipalities. Each living lab will be supported by the pooling of resources from the four research centers associated with the project. With its 3.88 million inhabitants, the Meuse-Rhine region is the ideal size for testing and deploying innovative NBS, provided that their applicability in various legal and technical contexts can be demonstrated. One of the project’s main innovations is thus to deploy solutions in vivo to observe their real-world effects in living labs established within various urban areas across the Meuse-Rhine region. To this end, NBS4U will test innovative and agile governance solutions, implemented by local governments or local communities, in order to reduce administrative costs and accelerate the deployment of nature-based solutions. The project’s main target groups are municipalities, local communities, public administrations, research centers, and service providers. |
Coordinateur : Jacques Teller ; Contacts ULiège : Roland Billen, Grégory Mahy et Manal Ginzarly |
The overall aim of Poly-DREAM is to boost the R&I, productivity and resilience of these market-focused SMEs by helping them use cutting-edge technologies for product development and manufacturing. To increase SME productivity, Poly-DREAM will establish a cross-border value chain and R&I ecosystem focused on Additive Manufacturing (AM, 3D printing). To achieve this, Poly-DREAM provides a market-focused platform with complementary know-how, infrastructure and hands-on training related to advanced additive manufacturing and polymer technologies. Only by pooling the MR region's specialist knowledge and infrastructure can Poly-DREAM develop an advanced, market-driven platform that will create momentum for region-wide collaboration and business cohesion. Poly-DREAM's innovative approach lies in its market-driven support for SMEs to use sustainable polymer AM to maximize their productivity (creating demonstrators and business cases with high market potential). Poly-DREAM's services to SMEs involve joint R&I to select the most suitable polymers, formulations and AM methods, through to scale-up, demonstration testing by SMEs (TRL7) and profitability creation. By leveraging our cross-border resources and complementary expertise, Poly-DREAM promotes the adoption of Industry 4.0 through cutting-edge MA technologies. Technologies, infrastructures, demonstrators and business cases will be developed for SMEs in the Meuse-Rhine region, in particular for those active in the healthcare and biotech sectors. Poly-DREAM will provide SMEs with state-of-the-art R&I in MA for product development, scale-up and business development. |
Philippe Lecomte, Christine Jérôme, Jean-Christophe Monbaliu |
Projects funded by Interreg VI Meuse-Rhin at the University of Liège
Acronym |
Title & Abstract |
Partner ULiège |
| CAREMORE aims to improve the resilience of healthcare professionals by addressing the challenges of staff shortages and job satisfaction. The project offers innovative training to improve individual, team and organizational resilience, contributing to a more sustainable and efficient healthcare system in the region. | Meryl Paquay, Alexandre Ghuysen | |
CHOOSE2REUSE (C2R) |
The energy-intensive and waste-generating construction sector faces major challenges in the Meuse-Rhine region. The C2R (Choose to Reuse) cross-border project aims to develop a circular ecosystem by facilitating the reuse of construction materials via a collaborative platform. It supports the ecological transition by connecting players in the sector, harmonizing practices and opening up new opportunities for SMEs. | Audrey Mertens, Catherine Elsen |
| Companies in the Meuse-Rhine Euregio lack talent trained in circularity in a cross-border context, while current training courses remain predominantly national. This project aims to create a trinational educational framework, co-constructed with companies, to offer interdisciplinary training aligned with the needs of the field. It will strengthen cooperation between universities and companies, while harmonizing the region's educational systems. | Michel Moutschen, Pierre Duysinx, Catherine Ghymers | |
| The main aim of the CYPRESS project is to make the Meuse-Rhine region the spearhead of sustainable, highly circular and resource-efficient production of new climate-neutral mobility solutions. | Pierre DUYSINX | |
| DigiPathConnect | The digitization of healthcare is a major challenge facing our society. Pathology plays a crucial role in hospital diagnostic workflows, but there is a shortage of experts. This project focuses on the digitization of pathology. Image sharing and analysis in combination with artificial intelligence (AI), known as "Digital Pathology" (DP), offer the potential for faster and more accurate diagnoses. | Pierre Geurts ; Raphaël Marée |
| ETCETERA | Europe faces a challenge in terms of digital competitiveness and sovereignty. Europe accounts for 5% of global AI (artificial intelligence) computing capacity, and 92% of cloud services rely on non-European providers. The ETCETERA project turns this challenge into an opportunity. By leveraging the computing needs of the Einstein Telescope (ET) as a driver of innovation, the project will design and validate AI workflows for multi-GB/s data streams, petabyte-scale storage, and rapid analysis for timely alerts. These solutions also support the regional transition to Industry 5.0 for data-driven monitoring, automation, and simulation. The project supports the Interreg Meuse-Rhine program by strengthening cross-border innovation capacity and building a shared digital infrastructure. It contributes to the major societal challenge of “Industrial Transition” by accelerating the adoption of trustworthy AI and advanced data processing (specific objective: as selected in the application). Cross-border cooperation is essential because strengths are distributed: Belgium excels in data science and embedded computing, the Netherlands in algorithm optimization and AI hardware co-design, and Germany in high-performance and distributed computing. ETCETERA pools these capabilities through joint developments, pilot projects, shared infrastructure, and training. The novelty lies in the integrated approach. Instead of isolated regional pilots, ETCETERA links ET to digital transformation and connects the AI Factory initiative into an interoperable ecosystem. The result: validated prototypes that reduce time-to-market and adoption risk. Target groups include data-intensive product/service companies, research organizations, and computing infrastructure providers. Without ETCETERA, the region risks missing out on the momentum surrounding ET and AI Factories, losing competitiveness in high-performance computing and AI, and forgoing skilled jobs as well as the attraction of talent and future investment. Demand is evidenced by support from industrial partners and regional innovation platforms, confirming interest from SMEs and support for the rapid adoption of tools |
Contact ULiège :Maxime Fays |
| FIT (Fitness Improving Technology) | The Meuse-Rhine (MR) region is establishing itself as a hub of innovation in muscle stem cell therapy, thanks to the FIT project, which brings together universities and SMEs around patentable technologies. This initiative aims to develop treatments for a variety of muscle diseases, based on cross-border clinical trials and personalized tools. Within three years, the aim is to position the MR region as a world leader in this field. |
Jo Caers |
| Flood Wisdom | Flood Wisdom improves flood forecasting and management capabilities in the Meuse-Rhine region, by developing innovative tools such as an early warning system. This strategic project brings together 12 partners and implements collaborative solutions to reduce the risks associated with extreme weather events, in response to climate change. |
Benjamin Dewals, Sébastien Erpicum, Geoffrey Houbrechts, Roland Billen |
| Interreg Meuse-Rhine (IMR) Blue Zone | Following the Blue Zone model (areas where people live longer thanks to a healthy lifestyle) and preventive medicine concepts, the project aims to explore the variables influencing a healthy IMR lifestyle, develop targeted practical guidelines for local actors to facilitate healthy IMR lifestyle behavior and improve health literacy at local level, especially among selected vulnerable groups. |
Alexandre Mouton |
| LivLabPRoFruit | The main objective of LivLabPRoFruit (Living Laboratory for Precision and Robotic Fruit Growing) is to create and operate an open living laboratory in which agrotechnology companies and fruit growers actively cooperate (i) to optimize the development process of technological components and machinery for precision and robotic fruit growing, and (ii) to accelerate the adoption of these applications in practice. The project focuses on pear cultivation (the most economically significant in Belgium and the Netherlands) and blueberry cultivation (generally increasing demand), as well as viticulture (growing acreage in our region). All of these crops are labor-intensive. This project will strengthen research and development capabilities by providing technology companies with a framework to innovate more effectively and successfully. It will promote and accelerate the adoption of new applications. It will contribute to making the MR region smarter. |
Coordination : Pcfruit vzw ; Contact ULiège : Frédéric Lebeau |
| MAS4TE | MAS4TE aims to create a cross-border energy exchange platform for prosumers. Based on blockchain and artificial intelligence technologies, it facilitates local energy trading and storage by integrating citizens into decentralized energy management, contributing to the energy transition in the Meuse-Rhine region. |
Roland Billen, Pierre-Henri Lefebvre, Bertrand Cornélusse |
| The aim of PFAS-resolve is to further develop promising new technologies that have been demonstrated at laboratory scale, and to implement them in field applications. Maastricht University has recently developed a biosensor technology capable of detecting PFOA at regulatory concentrations, while Bio2Clean has carried out several promising field trials in phytosanitary screening. Working with the engineering departments of the Fachhochschule Aachen and the Université de Liège, the aim is to transform these university technologies into demonstrators for field trials. End-users Geonius and Spaque will work with the consortium to define the device specifications. The Hygiene-Institut des Ruhrgebiets and Spaque will evaluate the sensor results using state-of-the-art laboratory techniques. |
Jean-Michel REDOUTE, François Dupont | |
REAL’s primary objective is to take the first step toward Industry 5.0 together with micro, small, and medium-sized enterprises (MSMEs) in the Meuse-Rhine region. Industry 5.0 is inherently interdisciplinary. For its successful adoption in the MR region, it is essential to break down the silos of knowledge and innovation that currently exist across borders. Within the consortium, academic partners bring together cutting-edge interdisciplinary expertise. Ecosystem partners engage SMEs, provide real-world feedback, and identify, engage, and connect innovation hubs (e.g., POM Limburg, Brightlands, etc.). REAL will integrate and translate Industry 5.0 technologies into concrete, practical solutions for SMEs. These solutions will be compiled into the REAL TOOLKITS, offering easy access to SMEs. SMEs also need strategic and practical support, as they cannot change everything at once. This is supported by the REAL COMPASS. REAL will test the COMPASS and TOOLKITS in 16 SMEs and implement them in an additional 60 SMEs, thereby directly supporting 76 SMEs. REAL will achieve these figures through massive mobilization (partner network + events/communication + innovation silos), followed by an implementation strategy that transforms mobilization into concrete action. REAL plans a post-project strategy including the creation of an I5.0 network bringing together innovation hubs and accelerators. |
Coordination : PXL ; Contacts ULiège : Nathalie Crutzen, Didier Van Caillie, Audrey Lebas |
|
RE-USE aims to accelerate the reuse of materials in construction to promote a circular economy. By overcoming obstacles related to data, legal aspects and practical implementation, the project is developing tools for integrating reuse into construction projects, in collaboration with regional and cross-border pilots. |
Roland Billen, Pierre-Henri Lefebvre | |
This project focuses on improving patient care via (1) the integration of home telemonitoring and (2) the use of this data and the improvement of data flow, cooperation/communication between primary care (GPs, care organizations) and secondary care (hospitals), cross-border and the patients themselves. |
Jean-Michel REDOUTE, François Dupont | |
VIAVIA will link tourist routes around the Roman remains of the Meuse-Rhine Euroregion (Via Belgica, Römerstrasse, Fruitspoor), creating a coherent, immersive tourism product. Nine cultural "hotspots" will be connected through multilingual storytelling, digital experiences and local initiatives to enrich the visitor experience and stimulate the regional economy. |
Roland Billen |
Projects funded by Interreg V A Meuse-Rhine at the University of Liège
Acronym |
Title & Abstract |
Partner ULiège |
| AACOMA | Accelerate Advanced Composite Manufacturing | Accelerate Advanced Composite Manufacturing : Composites were mainly developed for the aerospace industry for their exceptional combination of lightness and mechanical properties. Technical advances in materials design and advanced manufacturing processes (Industry 4.0) are paving the way for their use in many sectors. Acquiring knowledge in advanced material and process technologies, building demonstrators and testing them are essential steps that need to be evaluated before investing in new production lines. | Olivier BRULS |
| BC4P | Blockchain4Prosumers | Roland BILLEN |
| BuSyBee | From business to science to business in EMR+ | Didier Mattivi |
| Compas | COmprehensiveMultiprofessionalEducationfor improving, distributing and implementingPAtientSafety and maintenance of workforcein the EMR | Alexandre-Emmanuel GHUYSEN |
| Cross quality | Measuring the quality of cross-border cooperation in MRE | Roland BILLEN |
| Digital Twin Academy |
Academy of digital twins | Michaël SCHYNS |
| EMfloodResilience | Benjamin DEWALS | |
| EMR Connect (ECON) | Mario COOLS | |
| ET2SMEs |
Maximizing the economic and social impact of the Einstein Telescope (ET) in the Euregio Meuse-Rhine (EMR) | Didier Mattivi |
| E-TEST | Site and technology of the Einstein Telescope in the EMR: Recent detections of gravitational waves have opened a new window on the universe, in line with Einstein's work, offering an exciting future that will only be possible with a new generation of ultra-sensitive laser-interferometric gravitational observatories. This requires a large-scale, world-class underground infrastructure (300 m deep) covering around 50 km² in the area between the Netherlands, Germany and Belgium. Such a remarkable and unique international scientific infrastructure (the Einstein Telescope) will stimulate the socio-economic development of the region, and make a major contribution to boosting the competitiveness of local SMEs. The Einstein Telescope (ET) is currently in competition with three candidates, and the EMR site has been identified as a suitable location to host the ET. The Interreg EMR program therefore appears to be an ideal instrument to support this initiative. | Christophe COLLETTE |
| euPrevent PROFILE |
Preventing loneliness among the Euregio's senior citizens | Stéphane ADAM |
| EuPrevent SNA |
Subjective evaluation of consumers' harmful use of addictive substances in relation to objective data "social norms approach" as an innovative method of addiction prevention | Benoît PÉTRÉ |
| EUR.Friends | e(s) work(s) with e(s). Eur(egional)/(opean). Friends | Marie MAWHIN |
| EURLIPIDS | Edwin DE PAUW | |
| Food Screening EMR: New tools for sustainably producing healthy food cropsFood Screening EMR |
Discovering new tools for quality assurance in the food industry | Jean-Michel REDOUTE |
| GYM |
Generate your muscles: Maintaining muscle mass and strength is important for a healthy and sustainable life, but not for everyone. Muscle degradation affects 10-20% of the elderly population, leading to loss of function, reduced quality of life and sometimes even death. In all these cases, there is no effective treatment, and the development of a generic therapy to restore muscle mass and strength has a huge impact, both in terms of preventing severe suffering and improving quality of life. | Yves BEGUIN |
| i2CoRT | Innovation and implementation gas pedal for complex rehabilitation technologies | Jean-François KAUX |
| IKIC Public Safety | International Knowledge and Information Center for Public Safety | Alexandre-Emmanuel GHUYSEN |
| IMPACT |
International meeting place for the performing arts and creative technologies | Didier Mattivi |
| In Flow | Innovative flow chemistry for sustainable formulations: The main challenge of this R&D project for the formulation, characterization and engineering of biochemicals is to introduce new degradable packaging technologies for rapid, low-cost formulation. The three main objectives are (1) to set up an open technology platform; (2) to develop R&D infrastructure, technologies and protocols for the production of biodegradable capsules; and (3) to synthesize degradable biomaterials meeting end-user demands. |
Christine JEROME |
| LIVES - LV25 | Light vehicles 2025 | Pierre DUYSINX |
| N-POWER | Neighborhood empowerment | Jacques TELLER |
| OncoCare | Innovation and quality for patient-centered oncology management | Yves BEGUIN |
| Poly-Valve | Polymeric heart valve prosthesis for life "Creative chemistry for a sustainable future | Patrizio LANCELLOTTI |
| Projet Interreg SEE-V-Lab dans l’Eurégion Meuse-RhinSEE-V-Lab | Student entrepreneurship Euregio VentureLab | Bernard SURLEMONT |
| Terra Mosana | Improving the connectivity of the Meuse-Rhine Euregio's urban and architectural heritage through digital storytelling | Roland BILLEN |
| TREE | Training for integrating refugees in the euregioTREE | Training for the integration of refugees in the Euregio | Marianne POUMAY |
| Healthy aging | Virtual Institute for Lipid Research (VIRIL) | Renaud LOUIS |
| WearIT4COVID |
Portable real-time monitoring system for COVID-positive hospitalized patients in the Meuse-Rhine Euregio | Didier Mattivi |
| WearIT4Health | Integrated wearable technology for inpatient health monitoring in the Euregio Meuse-Rhine | Didier Mattivi |
TO ALL INTERREG PROJECTS AT ULIEGE

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